Iranian researchers tested 90 patients undergoing elective heart angioplasty, giving one group 500 milligrams (mg) curcumin, the second group 80 mg nano-curcumin, and the third a placebo. After eight weeks, both types of curcumin significantly improved cholesterol, triglyceride and LDL-C levels. They also boosted antioxidant levels, superoxide dismutase and glutathione, and reduced C-reactive protein levels, indicating less inflammation. The nano-curcumin, however, produced even better results in five of those indexes, leading the authors to conclude that the effects of curcumin on the nano formula may be more conducive for cardiac patients due to its high bioavailability. Nano-curcumin is made through a process that encapsulates the herb, allowing it to be metabolized better.